PMxEC Recent Pubulication (part)


  1. Cheng, Xiaoliang; Zhou, Tianyan; Li, Bo; Li, Mengyao; Li, Liang; Li, Zaiquan; Lu, Wei, Methotrexate synergizes with 5-aminoimidazole-4-carboxamide riboside in inhibiting cancer cell proliferation and increases 5-aminoimidazole-4-carboxamide riboside and its active metabolite in tumors, 2013, Acta Pharmacologic Sinica, Accepted
  2. Bi, Shanshan; Deng, Chenhui; Zhou, Tianyan; Guan, Zheng; Li, Liang; Li, Hanqing; Zhang, Liping; Yang, Lu; Lu, Wei, Remifentanil–sevoflurane interaction models of circulatory response to laryngoscopy and circulatory depression, 2013, British Journal of Anaesthesia, Epub ahead of print
  3. Cheng, Xiaoliang; Guo, Liping; Li, Zaiquan; Li, Liang; Zhou, Tianyan, Lu, Wei, A HPLC method for simultaneous determination of 5-aminoimidazole-4-carboxamide riboside and its active metabolite 5-aminoimidazole-4-carboxamide ribotide in tumor-bearing nude mice plasma and its application to pharmacokinetics study, 2013, Journal of Chromatography B, 915–916: 64–70
  4. Li, Mengyao; Li, Hanqing; Cheng, Xiaoliang;  Wang, Xipei; Li, Liang; Zhou, Tianyan. Lu, Wei, Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between Erlotinib and Gemcitabine, 2013, Pharmaceutical Research, 30: 1400-1408
  5. Zhou, Xuan; Shang, Dewei; Zhang, Tianlan; Li, Liang; Zhou, Tianyan; Lu, Wei, Modeling of Angiotensin II-Angiotensin-(1-7) Counterbalance in Disease Progression in Spontaneously Hypertensive Rats Treated With/Without Perindopril, 2012, Pharmacologic Research, 66: 177-184
  6. Li, Xingang; Li, Liang; Wang, Xipei; Ren, Yupeng; Zhou, Tianyan; Lu, Wei, Application of Model-Based Methods to Characterize Exenatide-Loaded Double-Walled Microspheres: In Vivo Release, Pharmacokinetic/Pharmacodynamic Model, and In Vitro and In Vivo Correlation, 2012, Journal of Pharmaceutical Sciences, 101(10): 3946-3961
  7. Xu, Jiaojiao; Chen, Ye; Li, Liang; Li, Zaiquan; Wang, Chenai; Zhou, Tianyan, Lu, Wei, An improved HPLC method for the quantitation of 3′-phosphoadenosine 5′-phosphate (PAP) to assay sulfotransferase enzyme activity in HepG2 cells, 2012, Journal of Pharmaceutical and Biomedical Analysis, 62: 182-186
  8. Ji, Xiwei; Chen, Ye; Li, Runtao; Zhou, Tianyan ; Lu, Wei, A high-sensitivity LC-MS/MS method for determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3, 3-diphenylpropyl ester hydrochloride in rat plasma and its application to pharmacokinetics study, 2012, Biomedical Chromatography, 26: 1196-1201
  9. Li, Xingang; Li, Liang; Zhou, Xuan; Chen, Ye; Ren, Yupeng; Zhou, Tianyan; Lu, Wei, Pharmacokinetic/ pharmacodynamic studies for exenatide in diabetic rats, 2012, Acta Pharmacologic Sinica, 33: 1379-1386
  10. Li, Liang; Li, Zaiquan; Deng, Chenhui; Ning, Miaoran; Li, Hanqing; Bi, Shanshan; Zhou, Tianyan and Lu, Wei, A Mechanism-based Pharmacokinetic/Pharmacodynamic Model for CYP3A1/2 Induction by Dexamethasone in Rats, 2012, Acta Pharmacologic Sinica, 33: 127-136
  11. Wang, Xipei; Shang, Dewei; Ribbing, Jakob; Ren, Yupeng; Deng, Chenhui; Zhou, Tianyan; Guo, Feng; Lu, Wei, Placebo effect model in asthma clinical studies–Longitudinal meta-analysis of forced expiratory volume in one second.  Pharmacology, 2012, European Journal of Clinical Pharmacology, 68: 1157–1166
  12. Li LJ,  Shang DW, Li WB, Guo W, Wang XP, Ren YP, Li AN, Fu PX, Ji SM, Lu W, Wang CY, Population Pharmacokinetics of Clozapine and its Main Metabolite Norclozapine in Chinese Patients with Schizophrenia, 2012, Acta Pharmacologic Sinica, 33(11): 1409-1416
  13. Wu, Ke-hua; Guo, Tao; Deng, Chen-hui; Guan, Zheng; Li, Liang; Zhou, Tian-yan; Lu, Wei, Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China, 2012, Acta Pharmacologic Sinica, 33(11): 1401-1408
  14. He DK, Wang L, Qin J, Zhang S, Lu W, Li L, Zhang JM, Bao WQ, Song XQ, Liu HT, Population pharmacokinetics of lamotrigine in Chinese children with epilepsy, 2012, Acta Pharmacologic Sinica, 33(11): 1417-23
  15. Wang HL, Yang L, Guo XY, Zhang LP, Bi SS, Lu W, Response surface analysis of sevoflurane-remifentanil interactions on consciousness during anesthesia, 2012, Chin Med J (Engl), 125(15): 2682-7
  16. Wang YH, Wang L, Lu W, Shang DW, Wei MJ, Wu Y, Population pharmacokinetics modeling of levetiracetam in Chinese children with epilepsy, 2012, Acta Pharmacologic Sinica, 33(6): 845-51,
  17. Zhang D, Wang Z, Zhao X, Lu W, Gu J, Cui Y, Pharmacokinetics, pharmacodynamics, tolerability and safety of single doses of bivalirudin in healthy Chinese subjects, 2011, Biol Pharm Bull, 34(12): 1841-8
  18. Ren YP, Deng CH, Wang XP, Zhou TY, Lu W, Comparison study of model evaluation methods: normalized prediction distribution errors vs. visual predictive check, 2011, Acta Pharmaceutical Sinica, 46(9): 1123-31
  19. Deng CH, Zhang GM, Bi SS, Zhou TY, Lu W, The therapeutic drug monitoring network server of tacrolimus for Chinese renal transplant patients, 2011, Acta Pharmaceutical Sinica, 46(7): 828-33
  20. Shang D, Wang X, Zhao X, Huang F, Tian G, Lu W, Zhou T, Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction, 2011, J Chromatogr B Analyt Technol Biomed Life Sci, 879(30): 3459-64
  21. LIU Ling, HUA Ying, ZHAO Wei-hong, LU Xin-tian, MA Yue-hong, LU Wei-wei, DU Jun-bao, Lu Wei, Population pharmacokinetics of high-dose methotrexate in childhood lymphoid malignancies, 2011, Chinese Journal of Practical Pediatrics, 26(2): 104-108
  22. Liang Li, Zai-Quan Li, Han-Qing Li, Shan-Shan Bi, Jiao-Jiao Xu, Bo Li, Tian-Yan Zhou, Wei Lu, Absolute quantification of induced mRNA expression of CYP3A1 and CYP3A2 in rat liver using quantitative real time PCR assay, 2011, Journal of Chinese Pharmaceutical Sciences, 20(6): 597-603
  23. Yang L, Wang HL, Zhang LP, Bi SS, Lu W, Yang BX, Guo XY, Population pharmacokinetics of rocuronium delivered by target-controlled infusion in adult patients, 2010, Chin Med J (Engl), 123(18): 2543-7
  24. Yang L, Wei B, Zhang LP, Bi SS, Lu W, Guo XY, Pharmacodynamic interaction between propofol and remifentanil on the tolerance response to electrical tetanus stimuli, 2010, Journal of Peking University (Health Science), 42(5): 547-53
  25. SHANG De-wei, WANG Xi-pei, DENG Chen-hui, BI Shan-shan, GUAN Zheng, ZHOU Tian-yan, LU Wei, Application of pharmacometrics in drug development and therapeutic drug monitoring, 2010, Journal of China Pharmaceutical University, 41(1): 91-96
  26. DENG Chen-hui, ZHANG Guan-min, BI Shan-shan, SHANG De-wei, ZHOU Tian-yan, LU Wei, Therapeutic Drug Monitoring Software of Tacrolimus for Chinese Renal Transplant Patients, 2010, Chinese Pharmaceutical Journal, 45(10): 775-780
  27. Guan Z,  Zhang GM,  Ma P,  Liu LH,  Zhou TY,  Lu W, Application of Fourier amplitude sensitivity test in Chinese healthy volunteer population pharmacokinetic model of tacrolimus, 2010, Acta Pharmaceutical Sinica, 45(7): 883-90
  28. Zhang LP,  Yang L,  Bi SS,  Lu W,  Zhang XH,  Zhai SD,  Duan LP, Population pharmacokinetics of remifentanil in patients undergoing orthotopic liver transplantation, 2009, Chin Med J (Engl), 122(9): 1032-8
  29. Zhang Y,  Xie J,  Chen WQ,  Zhou TY,  Lu W, Development of a sensitive high-performance liquid chromatographic method with simple extraction for simultaneous determination of huperzine A and huperzine B in the species containing lycopodium alkaloids, 2009, J AOAC Int, 92(4): 1060-3
  30. Zhao Y,  Duan JL,  Wu XM,  Jiang JY,  Lu W,  Zhang LP,  Wang J,  Meng XL,  Xu CY,  Jia DL,  Liu W,  Sheng XY, Two-stage analysis of pharmacokinetics of sufentanil administered by target-controlled infusion in Chinese patients, 2009, Chin Med J (Engl), 122(17): 1979-84
  31. Qiu XW,  Fu PX,  Wang CY,  Liu M,  Zhou TY,  Lu W, Population pharmacokinetics research of clozapine in Chinese schizophrenic patients, 2009, Acta Pharmaceutical Sinica, 44(7): 785-92
  32. ZHANG Xing-yi, CHEN Da-wei, JIN Jie, LU Wei, Artificial neural network parameters optimization software and its application in the design of sustained release tablets, 2009, Acta Pharmacologic Sinica, 10: 1156-64
  33. Zhang CY, Gu J, Li YZ, Lu W, Population pharmacokinetics of high-dose methotrexate administered in 329 children with acute lymphoblastic leukemia, 2008, Journal of Experimental Hematology, 16(1): 106-10
  34. Zhang S,  Wang L,  Lu W, Population pharmacokinetics of lamotrigine in Chinese children with epilepsy, 2008, Chinese Journal of Contemporary Pediatrics, 10(2): 105-9
  35. Liu YF,  Yang XW,  Lu W,  Xin XL, Determination and pharmacokinetic study of tussilagone in rat plasma by RP-HPLC method, 2008, Biomed Chromatogr, 22(11): 1194-200
  36. Zhang GM,  Li L,  Chen WQ,  Bi SS,  Liu X,  Zhang XL,  Lu W, Population pharmacokinetics of tacrolimus in Chinese renal transplant patients, 2008, Acta Pharmaceutical Sinica, 43(7): 695-701
  37. Hua Y,  Zhao WH,  Lu XT,  Yang LH,  Lu W, Investigation on individualized adjustment of target range of high-dose methotrexate, 2008, Chinese Journal of Pediatrics, 46(3): 203-8
  38. LI Liang, GUAN Zheng, MA Xin, JIU Xiang-fei, LU Wei, Simultaneous Determination of Dexamethasone, Testosterone and 6β-OH Testosterone in William’s Medium E, 2008, Chinese Pharmaceutical Journal, 11: 870-74
  39. ZHANG Chun-Yan, GU Jian, LI Yu-Zhen, LU Wei, Population Pharmacokinetics of High-dose Methotrexate Administered in 329 Children with Acute Lymphoblastic Leukemia, 2008, Journal of Experimental Hematology, 1: 106-10

  40. GUAN Zheng, BI Shan-shan, YANG Lu, ZHANG Li-ping, ZHOU Tian-yan, LU Wei, Progress in the study of response surface modeling in investigation of drug-drug interaction in anesthetic drugs, 2008, Acta Pharmaceutic Sinica, 12: 1171-78