Research Group

Faculty Student
        Prof. Wei Lu         Student
        Asso. Prof. Tianyan Zhou         Graduating student
        Liang Li  

Liang Li


  • Biography

  Liang Li, Ph.D. instructor in the Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center since August 2011. He received his Bachelor, Master and Ph.D. degree from School of Pharmaceutical Science, Peking University supervised by Prof. Wei Lu and Prof. Tianyan Zhou in 2006, 2008 and 2011, respectively. His Ph.D. program was supported by Pfizer Scholarship from Peking University/Pfizer Pharmacometrics Education Center. He studied in Department of Clinical Pharmacology and Pharmacometrics, China Research and Development Center (CRDC, Shanghai) as a visiting scholar from October 2011 to June 2013. He teaches Pharmaceutics, Biopharmaceutics and Pharmacokinetics etc. for undergraduates or graduates.
Email: Liliang@bjmu.edu.cn
Tex/Fax: +86-(10)-82801717


  • Research Interests
    • Mechanism-based Pharmacokinetic/Pharmacodynamic modeling and simulation
    • Application of Population Pharmacokinetics in drug research and development
    • Application of Model-based Meta-analysis in drug research and development
  • Recent Publications
    1. Li, Liang; Marshall, Scott; Xie, Rujia* and Lu,Wei*. An exploratory analysis of the Comparative Efficacy of Single Doses of Standard Analgesics in the Treatment of Postoperative Dental pain. (In preparation)
    2. Li, Liang; Marshall, Scott; Xie, Rujia* and Lu,Wei*. Model-based Meta-Analysis Demonstrating the Comparative Efficacy of Single Doses of Standard Analgesics in the Treatment of Postoperative Dental Pain. (In preparation)
    3. Li, Liang; Li, Zaiquan; Deng, Chenhui; Ning, Miaoran; Li, Hanqing; Bi, Shanshan; Zhou, Tianyan* and Lu, Wei*. Mechanism-based Pharmacokinetic/ Pharmacodynamic Model for CYP3A1/2 Induction by Dexamethasone in Rats. Acta Pharmacologica Sinica. 33, 127-136, 2012.
    4. Li, Liang; Li, Zaiquan; Li,Hanqing; Bi, Shanshan; Li, Bo; Xu, Jiaojiao; Zhou, Tianyan* and Lu,Wei*. Development of a quantitative real time PCR assay for absolute detection and quantification of CYP3A1 and CYP3A2 mRNA induction in rat liver. Journal of Chinese Pharmaceutical Sciences. 20(5), 597-603, 2011.
    5. (Li, Mengyao; Li, Hanqing; Cheng, Xiaoliang; Wang, Xipei; Li, Liang; Zhou, Tianyan; Lu, Wei. Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between Erlotinib and Gemcitabine. Pharmaceutical research. [Epub ahead of print], 2013.
    6. Li, Xingang; Li, Liang; Wang, Xipeng; Ren, Yupeng; Zhou, Tianyan*; Lu, Wei*. Application of Model-Based Methods to Characterize Exenatide-Loaded Double-Walled Microspheres: In Vivo Release, Pharmacokinetic/ Pharmacodynamic Model, and In Vitro and In Vivo Correlation. Journal of Pharmaceutical Sciences. 101(10), 3946-3961, 2012.
    7. Li, Xingang; Li, Liang; Zhou, Xuan; Chen, Ye; Ren, Yupeng; Zhou, Tianyan*; Lu, Wei*. Pharmacokinetic/ pharmacodynamic studies for exenatide in diabetic rats. Acta Pharmacologica Sinica. 33(11), 1379-86, 2012.
    8. Zhou, Xuan; Shang, Dewei; Zhang, Tianlan; Li, Liang; Zhou, Tianyan*; Lu, Wei*. Modeling of Angiotensin II-Angiotensin-(1-7) Counterbalance in Disease Progression in Spontaneously Hypertensive Rats Treated With/Without Perindopril. Pharmacological Research. 66, 177-184, 2012.
    9. Li, Hanqing; Li, Mengyao; Li, Zaiquan; Li, Liang; Bi, Shanshan; Deng, Chenhui; Chen, Rui; Zhou, Tianyan*. and Lu, Wei*. New synthetic route of two active isomeric metabolites of erlotinib and their bioactivity studies against several tumor cell lines. Chinese Journal of Chemistry 29(8), 1709-1714, 2011.
    10. Li, Mengyao; Wu, Qiong; Li, Hanqing; Ning, Miaoran; Chen, Ye; Li, Liang; Zhou, Tianyan*. and Lu, Wei*. A high-sensitive LC-MS/MS method to determine the concentrations of erlotinib and its active metabolite OSI-420 in BALB/c nude mice simultaneously and its application to a pharmacokinetic study. Journal of Chinese Pharmaceutical Sciences. 21, 296-303, 2012.
    11. Chen, Ye; Li, Hanqing; Xu, Jiaojiao; Jiu, Xiangfei; Deng, Chenhui; Li, Xingang; Li, Liang; Xu, Xiaoqing; Zhou, Tianyan*. and Lu, Wei*. Determination of metformin in diabetic rat plasma by an improved ion-pair high-performance liquid chromatography: Application to pharmacokinetic study, Journal of Chinese Pharmaceutical Sciences. 21, 211-218, 2012.
    12. Miaoran Ning, Liang Li, Jian Li, Zaiquan Li, Runtao Li, Tianyan Zhou*, Wei Lu*. In-vitro screen of reversible and time-dependent inhibition of CYP3A by TM208 and TM209 in rat liver microsomes. Acta Pharmaceutica Sinica B. 2(2), 179–185, 2012.
    13. Li, Hanqing; Chen, Ye; Li, Zaiquan; Deng, Chenhui; Li, Liang; Bi, Shanshan; Li, Mengyao; Zhou, Tianyan*; Lu, Wei*. A high performance liquid chromatography method for the quantitative determination of erlotinib in the plasma of tumor bearing BALB/c nude mice and its application in a pharmacokinetic study. Journal of Chinese Pharmaceutical Sciences. 20(3), 245-252, 2011