Publication (recent five years, part)


  1. Cheng, Xiaoliang; Zhou, Tianyan; Li, Bo; Li, Mengyao; Li, Liang; Li, Zaiquan; Lu, Wei, Methotrexate synergizes with 5-aminoimidazole-4-carboxamide riboside in inhibiting cancer cell proliferation and increases 5-aminoimidazole-4-carboxamide riboside and its active metabolite in tumors, 2013, Acta Pharmacologica Sinica, 34(7): 951-959, First author supported by Pfizer

  2. Bi, Shanshan; Deng, Chenhui; Zhou, Tianyan; Guan, Zheng; Li, Liang; Li, Hanqing; Zhang, Liping; Yang, Lu; Lu, Wei, Remifentanil–sevoflurane interaction models of circulatory response to laryngoscopy and circulatory depression, 2013, British Journal of Anaesthesia, 110(5): 729-740, First author supported by Pfizer

  3. Cheng, Xiaoliang; Guo, Liping; Li, Zaiquan; Li, Liang; Zhou, Tianyan, Lu, Wei, A HPLC method for simultaneous determination of 5-aminoimidazole-4-carboxamide riboside and its active metabolite 5-aminoimidazole-4-carboxamide ribotide in tumor-bearing nude mice plasma and its application to pharmacokinetics study, 2013, Journal of Chromatography B, 915–916: 64–70, First author supported by Pfizer

  4. Li, Mengyao; Li, Hanqing; Cheng, Xiaoliang;  Wang, Xipei; Li, Liang; Zhou, Tianyan. Lu, Wei, Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between Erlotinib and Gemcitabine, 2013, Pharmaceutical Research, 30: 1400-1408

  5. Zhou, Xuan; Shang, Dewei; Zhang, Tianlan; Li, Liang; Zhou, Tianyan; Lu, Wei, Modeling of Angiotensin II-Angiotensin-(1-7) Counterbalance in Disease Progression in Spontaneously Hypertensive Rats Treated With/Without Perindopril, 2012, Pharmacologic Research, 66: 177-184, First author supported by Pfizer

  6. Li, Xingang; Li, Liang; Wang, Xipei; Ren, Yupeng; Zhou, Tianyan; Lu, Wei, Application of Model-Based Methods to Characterize Exenatide-Loaded Double-Walled Microspheres: In Vivo Release, Pharmacokinetic/Pharmacodynamic Model, and In Vitro and In Vivo Correlation, 2012, Journal of Pharmaceutical Sciences, 101(10): 3946-3961, First author supported by Pfizer

  7. Xu, Jiaojiao; Chen, Ye; Li, Liang; Li, Zaiquan; Wang, Chenai; Zhou, Tianyan, Lu, Wei, An improved HPLC method for the quantitation of 3′-phosphoadenosine 5′-phosphate (PAP) to assay sulfotransferase enzyme activity in HepG2 cells, 2012, Journal of Pharmaceutical and Biomedical Analysis, 62: 182-186

  8. Ji, Xiwei; Chen, Ye; Li, Runtao; Zhou, Tianyan ; Lu, Wei, A high-sensitivity LC-MS/MS method for determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3, 3-diphenylpropyl ester hydrochloride in rat plasma and its application to pharmacokinetics study, 2012, Biomedical Chromatography, 26: 1196-1201

  9. Li, Xingang; Li, Liang; Zhou, Xuan; Chen, Ye; Ren, Yupeng; Zhou, Tianyan; Lu, Wei, Pharmacokinetic/ pharmacodynamic studies for exenatide in diabetic rats, 2012, Acta Pharmacologic Sinica, 33: 1379-1386, First author supported by Pfizer

  10. Li, Liang; Li, Zaiquan; Deng, Chenhui; Ning, Miaoran; Li, Hanqing; Bi, Shanshan; Zhou, Tianyan and Lu, Wei, A Mechanism-based Pharmacokinetic/Pharmacodynamic Model for CYP3A1/2 Induction by Dexamethasone in Rats, 2012, Acta Pharmacologic Sinica, 33: 127-136, First author supported by Pfizer

  11. Wang, Xipei; Shang, Dewei; Ribbing, Jakob; Ren, Yupeng; Deng, Chenhui; Zhou, Tianyan; Guo, Feng; Lu, Wei, Placebo effect model in asthma clinical studies–Longitudinal meta-analysis of forced expiratory volume in one second.  Pharmacology, 2012, European Journal of Clinical Pharmacology, 68: 1157–1166, First author supported by Pfizer

  12. Li LJ,  Shang DW, Li WB, Guo W, Wang XP, Ren YP, Li AN, Fu PX, Ji SM, Lu W, Wang CY, Population Pharmacokinetics of Clozapine and its Main Metabolite Norclozapine in Chinese Patients with Schizophrenia, 2012, Acta Pharmacologic Sinica, 33(11): 1409-1416, First author supported by Pfizer

  13. Wu, Ke-hua; Guo, Tao; Deng, Chen-hui; Guan, Zheng; Li, Liang; Zhou, Tian-yan; Lu, Wei, Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China, 2012, Acta Pharmacologic Sinica, 33(11): 1401-1408

  14. Wenqian Chen, Yanqing Zhang, Junbo Xie, Tianyan Zhou, Wei Lu, SIMULTANEOUS DETERMINATION OF SIX PHENOLIC COMPOUNDS IN GUANXIN II PRESCRIPTION BY HPLC/MS/MS, 2012, Journal of Liquid Chromatography & Related Technologies, 35: 757–767

  15. He DK, Wang L, Qin J, Zhang S, Lu W, Li L, Zhang JM, Bao WQ, Song XQ, Liu HT, Population pharmacokinetics of lamotrigine in Chinese children with epilepsy, 2012, Acta Pharmacol Sinica, 33(11): 1417-23

  16. Wang HL, Yang L, Guo XY, Zhang LP, Bi SS, Lu W, Response surface analysis of sevoflurane-remifentanil interactions on consciousness during anesthesia, 2012, Chin Med J (Engl), 125(15): 2682-7

  17. Wang YH, Wang L, Lu W, Shang DW, Wei MJ, Wu Y, Population pharmacokinetics modeling of levetiracetam in Chinese children with epilepsy, 2012, Acta Pharmacol Sinica, 33(6): 845-51,

  18. LU He-qi, LU Wei, WANG Zhong, ZHANG Ling, WEI Ya-chuan, Applications of Pharmacokinetic/pharmacodynamic in prescriptions related research of traditional Chinese medicine, 2012, Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 18(9): 1040-1043

  19. GUO Tao, SUN Zuo-ming, GUAN Zheng, XIA Dong-ya, YANG Lu, ZHOU Tian-yan, LU Wei, Population Pharmacokinetics of Omeprazole in Healthy Volunteers of Different Nationalities in China by NONMEM, 2012, Pharmaceutical Journal of Chinese People’s Liberation Army, 28(5): 392-396

  20. LIU Jing, SHANG De-wei, REN Yu-peng, TIAN Gan-zhong, XU Jiao-jiao, ZHOU Tian-yan, LU Wei, Population Pharmacokinetics of Ambroxol Hydrochloride in Chinese Healthy Male Subjects, 2012, Chinese Pharmaceutical Journal, 47(3): 218-223

  21. WANG Hui-ling, YANG Lu, ZHANG Li-ping, GUO Xiang-yang, BI Shan-shan, LU Wei, Pharmacodynamic interaction between sevoflurane and remifentanil regarding tolerance of responses to electrical tetanus stimuli, 2012, Chinese Journal of New Drugs, 21(9): 1020-1026

  22. Ye Chen, Han-Qing Li, Jiao-Jiao Xu, Xiang-Fei Jiu, Chen-Hui Deng, Xin-Gang Li, Liang Li, Xiao-Qing Xu, Tian-Yan Zhou, Wei Lu, Determination of metformin in diabetic rat plasma by an improved ion-pair high-performance liquid chromatography: application to a pharmacokinetic study, 2012, Journal of Chinese Pharmaceutical Sciences, 21(3): 211-218

  23. Peng Xu, Wen-Si Lin, Chuan-Jun Zhu, Ke-Lin Liu, Ying Chang, Yu-Xin Cui, Xiao-Mei Ling, Wei Lu, Identification of dimethylamphetamine in a suspect exhibit, 2012, Journal of Chinese Pharmaceutical Sciences, 21(4): 355-359

  24. Meng-Yao Li, Qiong Wu, Han-Qing Li, Miao-Ran Ning, Ye Chen, Liang Li, Tian-Yan Zhou, Wei Lu, A sensitive LC-MS/MS method to determine the concentrations of erlotinib and its active metabolite OSI-420 in BALB/c nude mice plasma simultaneously and its application to a pharmacokinetic study, 2012, Journal of Chinese Pharmaceutical Sciences, 21(4): 296-303

  25. WANG Ying-hui, WANG Li, LU Wei, WEI Min-ji, WU Ye, SHANG De-wei, WANG Yun-xiu, Population pharmacokinetic analysis of levetiracetam in Chinese children with epilepsy, 2012, Chinese Journal of Practical Pediatrics, 27(7): 517-522

  26. XU Peng, LI Xiaona, LIU Kelin, LING Xiaomei, LU Wei, UFLC DETERMINATION OF THE CONTENT OF JWH-018 IN NEW “K2” SPICE, 2012, Chinese Journal of Drug Dependence, 21(4): 282-285

  27. Chen, Wenqian; Zhang, Yanqing; Xie, Junbo; Zhou, Tianyan; Lu, Wei, Antagonism activity against acute myocardial ischemia of paeoniflorin and its pharmacokinetic/ pharmacodynamic(PK/PD) modeling in rats, 2011, Journal of Medicinal Plants Research, 5(29):  6496-6501

  28. Zhang D, Wang Z, Zhao X, Lu W, Gu J, Cui Y, Pharmacokinetics, pharmacodynamics, tolerability and safety of single doses of bivalirudin in healthy chinese subjects, 2011, Biol Pharm Bull, 34(12): 1841-8

  29. Ren YP, Deng CH, Wang XP, Zhou TY, Lu W, Comparison study of model evaluation methods: normalized prediction distribution errors vs. visual predictive check, 2011, Acta Pharmaceutical Sinica, 46(9): 1123-31, First author supported by Pfizer

  30. Deng CH, Zhang GM, Bi SS, Zhou TY, Lu W, The therapeutic drug monitoring network server of tacrolimus for Chinese renal transplant patients, 2011, Acta Pharmaceutical Sinica, 46(7): 828-33, First author supported by Pfizer

  31. Shang D, Wang X, Zhao X, Huang F, Tian G, Lu W, Zhou T, Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction, 2011, J Chromatogr B Analyt Technol Biomed Life Sci, 879(30): 3459-64, First author supported by Pfizer

  32. Xiang-Fei Jiu, De-Wei Shang, Ye Chen, Xin-Gang Li, Xiao-Meng Wan, Tian-Yan Zhou, Wei Lu, A high performance liquid chromatography method for the quantitative determination assay of sitagliptin in rat plasma and its application in pharmacokinetics study, 2011, Journal of Chinese Pharmaceutical Sciences, 20(1): 63-69

  33. LIU Ling, HUA Ying, ZHAO Wei-hong, LU Xin-tian, MA Yue-hong, LU Wei-wei, DU Jun-bao, Lu Wei, Population pharmacokinetics of high-dose methotrexate in childhood lymphoid malignancies, 2011, Chinese Journal of Practical Pediatrics, 26(2): 104-108

  34. Han-Qing Li, Ye Chen, Zai-Quan Li, Chen-Hui Deng, Liang Li, Shan-Shan Bi, Meng-Yao Li, Tian-Yan Zhou, Wei Lu, high performance liquid chromatography method for the quantitative determination of erlotinib in the plasma of tumor bearing BALB/c nude mice and its application in a pharmacokinetic study, 2011, Journal of Chinese Pharmaceutical Sciences, 20(3): 245-252

  35. SHI Jie, GUO Tao, XIA Dong-ya, XU Ning-ning, DENG Chen-hui, BI Shan-shan, ZHOU Tian-yan, LU Wei, Population Pharmacokinetics of Zolpidem Tartrate Tablets in Healthy Volunteers of Five Different Nationalities in China, 2011, Chinese Pharmaceutical Journal, 46(11): 850-857

  36. Liang Li, Zai-Quan Li, Han-Qing Li, Shan-Shan Bi, Jiao-Jiao Xu, Bo Li, Tian-Yan Zhou, Wei Lu, Absolute quantification of induced mRNA expression of CYP3A1 and CYP3A2 in rat liver using quantitative real time PCR assay, 2011, Journal of Chinese Pharmaceutical Sciences, 20(6): 597-603, First author supported by Pfizer

  37. Xu CY, Wu XM, Jiang JY, Lu W, Effect of remifentanil on propofol pharmacokinetics with target controlled infusion in elderly patients, 2010, Journal of Peking University (Health Science), 42(6): 734-8,

  38. Yang L, Wang HL, Zhang LP, Bi SS, Lu W, Yang BX, Guo XY, Population pharmacokinetics of rocuronium delivered by target-controlled infusion in adult patients, 2010, Chin Med J (Engl), 123(18): 2543-7

  39. Yang L, Wei B, Zhang LP, Bi SS, Lu W, Guo XY, Pharmacodynamic interaction between propofol and remifentanil on the tolerance response to electrical tetanus stimuli, 2010, Journal of Peking University (Health Science), 42(5): 547-53

  40. ZHANG Xing-yi, CHEN Da-wei, LU Wei, Comparison of several statistic designs in the development of ligustrazine hydrochloride(TMPH) sustained release formulations, 2010, Chinese Journal of New Drugs, 19(5): 365-371

  41. SHANG De-wei, WANG Xi-pei, DENG Chen-hui, BI Shan-shan, GUAN Zheng, ZHOU Tian-yan, LU Wei, Application of pharmacometrics in drug development and therapeutic drug monitoring, 2010, Journal of China Pharmaceutical University, 41(1): 91-96, First author supported by Pfizer

  42. ZHANG Xing-yi, ZHAO Ya-nan, WANG Yue-ran, ZHANG Qiang, LU Wei, Establish the population pharmacokinetics model of azithromycin in Chinese healthy volunteers, 2010, The Chinese Journal of Clinical Pharmacology, 26(2): 106-110

  43. DENG Chen-hui, ZHANG Guan-min, BI Shan-shan, SHANG De-wei, ZHOU Tian-yan, LU Wei, Therapeutic Drug Monitoring Software of Tacrolimus for Chinese Renal Transplant Patients, 2010, Chinese Pharmaceutical Journal, 45(10): 775-780, First author supported by Pfizer

  44. SUN Chuan-jiang, GU Miao-ning, LIANG Li-li, BI Shan-shan, LU Wei, Opioid-Volatile pharmacodynamic interaction:a response surface analysis with sevoflurane and sufentanil as prototypes, 2010, Chinese Journal of New Drugs, 19(22): 2070-2076

  45. Guan Z,  Zhang GM,  Ma P,  Liu LH,  Zhou TY,  Lu W, Application of Fourier amplitude sensitivity test in Chinese healthy volunteer population pharmacokinetic model of tacrolimus, 2010, Acta Pharmaceutical Sinica, 45(7): 883-90

  46. Peng Zhen, Xiao-Jing Fan, Liang Ma, Zheng Guan, Wei Lu, Xin Hu, Application of fuzzy analytical method in the optimization of liposome preparation by orthogonal experiments, 2009, Journal of Chinese Pharmaceutical Sciences, 18(1): 37-42

  47. XU Ning-ning, CHANG Xin-yu, GUO Tao, XIA Dong-ya, WU Ke-hua, DENG Chen-hui, BI Shan-shan, ZHOU Tian-yan, LU Wei, Population Pharmacokinetics of Tinidazole in Five Different Ethnic Populations of China, 2009, Chinese Pharmaceutical Journal, 44(9): 692-698

  48. Zhao Y,  Wu XM,  Duan JL,  Sheng XY,  Liu W,  Lu W,  Zhang LP,  Xu CY, Pharmacokinetics of sufentanil administered by target-controlled infusion in Chinese surgical patients, 2009, Chin Med J (Engl), 122(3): 291-5

  49. Zhang LP,  Yang L,  Bi SS,  Lu W,  Zhang XH,  Zhai SD,  Duan LP, Population pharmacokinetics of remifentanil in patients undergoing orthotopic liver transplantation, 2009, Chin Med J (Engl), 122(9): 1032-8

  50. Zhang Y,  Xie J,  Chen WQ,  Zhou TY,  Lu W, Development of a sensitive high-performance liquid chromatographic method with simple extraction for simultaneous determination of huperzine A and huperzine B in the species containing lycopodium alkaloids, 2009, J AOAC Int, 92(4): 1060-3

  51. Zhao Y,  Duan JL,  Wu XM,  Jiang JY,  Lu W,  Zhang LP,  Wang J,  Meng XL,  Xu CY,  Jia DL,  Liu W,  Sheng XY, Two-stage analysis of pharmacokinetics of sufentanil administered by target-controlled infusion in Chinese patients, 2009, Chin Med J (Engl), 122(17): 1979-84

  52. Qiu XW,  Fu PX,  Wang CY,  Liu M,  Zhou TY,  Lu W, Population pharmacokinetics research of clozapine in Chinese schizophrenic patients, 2009, Acta Pharmaceutical Sinica, 44(7): 785-92

  53. ZHANG Xing-yi, CHEN Da-wei, JIN Jie, LU Wei, Artificial neural network parameters optimization software and its application in the design of sustained release tablets, 2009, Acta Pharmacologic Sinica, 10: 1156-64

  54. Zhang yanqing, Xie Junbo, Chen Wenqian, Deng Chenhui, Jiu Xiangfei, Zhou Tianyan, Lu Wei, Optimization the preparation of huperzine liposome by orthogonal test, 2009, Chinese Traditional and Herbal Drugs, 40(6): 896-98

  55. LIU Xiao, ZHANG Xiang-lin, ZHANG Lei, LI Peng-mei, LI Kai-peng, LU Wei, A Validation Study of Three Selected Methods Routinely Used For Measurement of Cyclosporine A, 2009, Chinese Pharmaceutical Journal, 44(10): 790-94

  56. Zhang CY, Gu J, Li YZ, Lu W, Population pharmacokinetics of high-dose methotrexate administered in 329 children with acute lymphoblastic leukemia, 2008, Journal of Experimental Hematology, 16(1): 106-10

  57. Zhang S,  Wang L,  Lu W, Population pharmacokinetics of lamotrigine in Chinese children with epilepsy, 2008, Chinese Journal of Contemporary Pediatrics, 10(2): 105-9

  58. Hua Y, Wang F, Zhao W, Lu W, Zhang H, Li J, Ding J, Lu X, Nonmuscle myosin heavy chain 9 gene mutations related disease: a family report, 2008, Journal of Peking University (Health Science), 40(2): 160-4

  59. Liu YF,  Yang XW,  Lu W,  Xin XL, Determination and pharmacokinetic study of tussilagone in rat plasma by RP-HPLC method, 2008, Biomed Chromatogr, 22(11): 1194-200

  60. Zhang GM,  Li L,  Chen WQ,  Bi SS,  Liu X,  Zhang XL,  Lu W, Population pharmacokinetics of tacrolimus in Chinese renal transplant patients, 2008, Acta Pharmaceutical Sinica, 43(7): 695-701

  61. Hua Y,  Zhao WH,  Lu XT,  Yang LH,  Lu W, Investigation on individualized adjustment of target range of high-dose methotrexate, 2008, Chinese Journal of Pediatrics, 46(3): 203-8

  62. ZUO Ying-xi, LI Liang, LU Wei, LIU Gui-lan, JIA Yue-ping, Determination of 1-β-D-arabinofuranosylcytosine incorporation into DNA in vivo by HPLC, 2008, Chinese Journal of Hospital Pharmacy, 28(9): 718-21

  63. LI Liang, GUAN Zheng, MA Xin, JIU Xiang-fei, LU Wei, Simultaneous Determination of Dexamethasone, Testosterone and 6β-OH Testosterone in William’s Medium E, 2008, Chinese Pharmaceutical Journal, 11: 870-74, First author supported by Pfizer

  64. Wen-Qian Chen, Yu-Hui Hu, Yan-Qing Zhang, Guan-Min Zhang, Liang Li, Wei-Ning Yang, Wei Lu, Population pharmacokinetics of paeoniflorin in guanxin Ⅱ prescription, 2008, Journal of Chinese Pharmaceutical Sciences, 1: 55-63

  65. Guan-Min Zhang, Wen-Qian Chen, Liang Li, Yu-Hui Hu, Yan-Qing Zhang, Hong Yi, Hua Yang, Wei Lu, Population pharmacokinetic analysis of baicalin after oral administration of different Shuang-Huang-Lian formulations to rats, 2008, Journal of Chinese Pharmaceutical Sciences, 1: 46-54

  66. Yang Lu, Bi Shanshan, Lu Wei, Yang Baxian, Pharmacodynamic Interactions between Remifentanil and Sevoflurane during General Anesthesia for Laparoscopic Operations, 2008, Chinese Journal of Minimally Invasive Surgery, 4: 345-48

  67. SUN Li li, SI Tian mei, LIU Yi, YANG Qin, ZHAI Suo di, LU Wei, Population pharmacokinetics of citalopram by NONMEM, 2008, The Chinese Journal of Clinical Pharmacology, 24(2): 151-56

  68. ZHANG Chun-Yan, GU Jian, LI Yu-Zhen, LU Wei, Population Pharmacokinetics of High-dose Methotrexate Administered in 329 Children with Acute Lymphoblastic Leukemia, 2008, Journal of Experimental Hematology, 1: 106-10

  69. ZHOU YING, CUI Yi-MIN, LU Wei, Individual medicine of cyclosporine: a case report, 2008, Chinese Pharmaceutical Journal, 24: 1925-26

  70. GUAN Zheng, BI Shan-shan, YANG Lu, ZHANG Li-ping, ZHOU Tian-yan, LU Wei, Progress in the study of response surface modeling in investigation of drug-drug interaction in anesthetic drugs, 2008, Acta Pharmaceutic Sinica, 12: 1171-78